PRP and PRF Injections in Riga: How the Procedure Works and What to Expect

Photo: freepik.com/Freepik
Natural beauty treatments and facial skin rejuvenation using the body’s own resources are becoming increasingly popular. Instead of relying solely on synthetic substances, we can use our own blood to improve the appearance, health, and radiance of our skin. This approach is safe and provides long-lasting results, as the body isn’t burdened with anything foreign, but many still have questions—how does it actually work, and does it hurt?
If you’re currently looking for information or considering PRP and PRF injections in Riga, it’s worth learning about the step-by-step process and what sensations to expect—as explained below by Jevgenija Vladimirova, a dermatologist at the Adoria Health and Beauty Center.
In this article, you will learn:
- How blood cells activate the skin’s internal resources and stimulate regeneration processes.
- What exactly happens in the treatment room—from blood collection to the end of the procedure.
- Whether the procedure is painful and why it can only be performed in a medical facility.
Why is the body able to restore skin structure with the help of blood?
To fully understand the high effectiveness of this method, it is worth taking a closer look at biological processes. The body possesses a natural ability to heal itself, and platelets—blood cells responsible for tissue regeneration—play a key role in this process. Whenever tissue damage occurs, it is the platelets that “rush to the scene” to promote healing.
The procedure is based on the targeted use of this natural potential. By injecting a concentrated platelet preparation into problem areas—whether they be wrinkles, scars, or skin that has lost its tone—tissue regeneration is stimulated at the cellular level. The moment the prepared solution reaches the dermis, the platelets begin to release growth factors. These bioactive substances act as a powerful signal for surrounding cells to become active. However, to achieve a specific therapeutic goal, specialists distinguish between two technologically distinct forms:
- PRP (Platelet-Rich Plasma): an anticoagulant is used during the preparation process to prevent the blood from clotting, resulting in liquid plasma. This ensures rapid release of growth factors and an immediate “energy boost” for cells, making it ideal for treating large areas (such as the scalp or the entire face) using mesotherapy techniques.
- PRF (Platelet-Rich Fibrin): is obtained without chemical additives by centrifuging blood at a slower speed. This results in a natural fibrin matrix that contains not only platelets, but also leukocytes and stem cells. This “scaffold” ensures a slow and sustained release of growth factors (for up to 7 days), promoting deeper regeneration and even slight volume restoration, for example, in the under-eye area.
As a result, fibroblasts are activated and begin to intensively produce new collagen and elastin—proteins that ensure skin firmness and an elastic framework. At the same time, microcirculation improves, ensuring better oxygen supply to the tissues. Thus, by choosing PRP and PRF injections, the patient does not merely achieve a temporary visual improvement, but triggers deep, physiological regeneration processes that deliver natural and long-lasting results.

Photo: freepik.com/Freepik
What does a visit to a specialist involve, step by step?
Fear often stems from a lack of knowledge, so it’s important to know exactly what will happen during the procedure. The entire process is fairly simple, sterile, and usually takes no more than an hour.
- Blood draw: it all starts much like a routine blood test. A very small amount of blood is drawn from a vein—usually one or two small vials.
- Preparation: the vials are placed in a special device—a centrifuge. It spins very quickly and separates the blood into layers. We only need the layer containing the “golden” cells and plasma, while the red blood cells are separated out because they are not used in the procedure.
- Administration: Once the preparation is ready, a specialist injects it into the skin using a very fine needle. The injections are numerous and precise so that the beneficial substances reach every area where they are needed—whether it’s the facial skin, neck, or scalp to stimulate hair growth.
When can visible results be expected, and how long do they last?
It is important to understand that autologous blood injections work differently than traditional fillers. Since the method is based on biological tissue stimulation rather than mechanical wrinkle filling, the results do not appear overnight.
The first positive changes—a healthier skin tone and reduced dryness—are usually noticeable about 2–3 weeks after the first procedure. However, to assess a real improvement in skin structure, restoration of density, and a lifting effect, a full cell renewal cycle must elapse. The longevity of the results depends on the patient’s age, lifestyle, and the initial condition of the skin, but on average, the effect lasts:
- In facial skin aesthetics: after completing a full course, the results last approximately 6 to 12 months. To prolong this, maintenance procedures are recommended.
- In trichology (hair treatment): a reduction in hair loss is often observed after just 2–3 sessions, but new hair growth and structural improvement are long-term processes that require regular therapy.
How often does the procedure need to be repeated?
To achieve the most effective and long-lasting results, specialists recommend undergoing the procedure as a course of treatments rather than as a single session. This allows the tissues to continuously receive regeneration signals and accumulate the positive effects.
- Number of procedures: On average, a course of 3 to 6 procedures is recommended.
- Interval: A break of 3 to 4 weeks should generally be observed between visits.
- Maintenance: After completing the course, to maintain the achieved results, it is recommended to undergo one maintenance procedure every six months or once a year.
In what cases is the procedure not recommended?
Although PRP and PRF injections are considered one of the safest methods in aesthetic medicine, there are certain situations in which they should not be performed or are not recommended. Before the procedure, the doctor always carefully assesses your health to rule out any risks. The main contraindications are:
- Blood disorders: thrombocytopenia (low platelet count), anemia, or blood clotting disorders, as the procedure will not be effective or may be dangerous in such cases.
- Acute infections: fever, viral infections, or active inflammatory processes (e.g., herpes virus) in the planned injection area.
- Oncological conditions: the procedure is contraindicated in cases of malignant tumors.
- Pregnancy and breastfeeding: although the method is natural, a woman’s hormonal balance is unstable during this period, so any invasive aesthetic procedures are postponed.
- Medication use: The use of nonsteroidal anti-inflammatory drugs or blood-thinning medications can affect platelet function, so it is essential to inform your doctor about this.
Why is this method recommended in combination with other procedures?

Photo: adoria.lv
Although PRP and PRF injections in Riga are becoming increasingly popular due to their natural effects and safety, in aesthetic medicine and beauty care, the most convincing long-term results can be achieved through a comprehensive approach.
PRP and PRF injections act as powerful biostimulators that trigger tissue regeneration; however, for cells to regenerate fully, they require a favorable physiological environment and resources. Therefore, specialists often develop a treatment plan designed to create a synergistic effect.
- Biorevitalization: Dehydrated or dry skin is unable to respond fully to stimulation because metabolic processes in the cells are slowed down. Hyaluronic acid injections restore the dermis’s moisture reserves and deeply hydrate the tissues. In a hydrated environment, growth factors released by platelets can function much more effectively, significantly improving the final result of the procedure and skin elasticity.
- Mesotherapy: To ensure high-quality collagen synthesis, the skin needs “building materials.” This method allows for the introduction of cocktails of vitamins, amino acids, peptides, and minerals into the dermis. While mesotherapy supplies cells with the necessary nutrients, plasma injections actively stimulate the use of these substances in tissue regeneration.
- Botulinum toxin injections: these methods work at different levels and complement each other perfectly. Botulinum toxin relaxes the muscles, preventing the formation of dynamic expression lines, while PRP or PRF injections improve the skin’s quality, density, and color directly in the area of the wrinkles. This results in both a smoother complexion and a healthier skin structure.
What should you consider when choosing a specialist?

Photo: adoria.lv
When looking for a place to get PRP and PRF injections in Riga, the most important criterion is the assurance that the procedure is performed by a qualified medical professional. Only a certified specialist has in-depth knowledge of facial anatomy, enabling them to precisely determine the depth and location of the injections to ensure maximum effectiveness without the risk of complications.
Similarly, in professional practice, a thorough health assessment and medical history review are always conducted before the procedure, including a discussion of medications currently being taken, and precise recommendations are provided for proper at-home skin care, which is an integral part of achieving lasting results.
Where can I schedule a consultation and procedure?
The Adoria Health and Beauty Center offers PRP and PRF injections in Riga, performed by experienced and knowledgeable dermatologists qualified in aesthetic dermatology. To learn more about the procedures and schedule an appointment, please call +371 67 315 000 or fill out the application form on our website. Entrust your beauty and health to experienced professionals in their field!